Docking analysis demonstrated the presence of bioactive compounds inhibited TNFa, HER2, and MMP9 as being the goal protein. The molecular dynamic consequence was confirmed utilizing molecular dynamic and it reveals that β-asarone conversation was steady from MMP9 and TNF protein showed by the lower RMSD worth. The research observed the investigated bioactive compounds of Piper crocatum contain the activity of anti-cancer by way of the inhibition of TNFa and MMP9 protein. Nevertheless, even further exploration even now really should be carried out to verify the prediction outcomes of the In Silico review.
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